Kathy Griffin

Though her humor may be wicked, Griffin hopes people understand that no malice is intended by it. "I'm genuinely a fan of most of the people I trash in the act," said Griffin in an interview. "I really, really try and focus on making fun of people for their behavior. I'm not so into making fun of someone for the way they look, or something that's out of their control." Her favorite celebrity topics are plastic surgery, Scientology, drunkenness, substance abuse, snooty attitudes, eating disorders, and stars whose sexual orientation is disputed. Among Griffin's staples are Paris Hilton, Clay Aiken, Barbara Walters, Whitney Houston, Larry David, Celine Dion, Gwyneth Paltrow, Jerry Seinfeld, Star Jones, Paula Abdul, Sharon Stone, Oprah Winfrey, Britney Spears, Ryan Seacrest, Lindsay Lohan, Miley and Billy Ray Cyrus, Bravo's Real Housewives, Kirstie Alley, Sarah Palin, Michele Bachmann, Elisabeth Hasselbeck, Uma Thurman and Renée Zellweger.

Griffin is sometimes the object of her own humor, particularly with regard to her D-list status. While Griffin paints herself as a Hollywood outsider, she has a group of close celebrity friends such as Rosie O'Donnell, Joan Rivers, Jerry Seinfeld, Gloria Estefan, Whoopi Goldberg, Jennifer Coolidge, Rachel True, Larry David, Ricky Gervais, Anderson Cooper, Cher and Lance Bass. Griffin's longtime friendship with Bass was the catalyst for a feud between her and gossip blogger Perez Hilton, in which Griffin expressed anger over Hilton's "outing" of Bass on his website, calling Hilton's attacks on Bass "mean" and "unfunny". Hilton responded by saying that Griffin's anger was hypocritical, considering all of the gay jokes she makes about Clay Aiken in her stand-up routines. Read Less