Sara Gilbert

Her contribution was considered so important to Roseanne that the show's producers juggled storylines and taping schedules to allow her to study at Yale University while remaining part of the cast, shooting remote segments of Darlene at a soundstage in New York. Read Less

The sitcom was canceled after one season, when the WB and UPN networks merged to become The CW and had to drop a number of shows. She also had a recurring role on the short-lived CBS sitcom The Class as Fern Velch.<br /><br /> Since 2007 she has appeared in a number of episodes of the CBS TV series The Big Bang Theory as Leslie Winkle, a scientist friend of Leonard Hofstadter, who is played by Johnny Galecki, who had previously played Gilbert's love interest David Healy on Roseanne. Starting with the second episode of the second season of The Big Bang Theory, Gilbert was elevated to the show's main cast, portraying once again a potential love interest of Galecki's character, and at one point a love interest to Howard Wolowitz (Simon Helberg). Read Less